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1. Leuk Lymphoma. 2008 Nov;49(11):2222-3. 2. Blood. 2008 Oct 15;112(8):3348-54. 3. Pharm Res. 2008 Apr;25(4):827-35.Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein. Tissue specificity: Widely expressed with high level in liver. |