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1. Nat Cell Biol. 2006 Jun;8(6):623-30.
2. Int J Hematol. 2007 Dec;86(5):429-37.
3. Nat Genet. 2008 Aug;40(8):955-62.PRDM1/Blimp1 is a repressor of beta-interferon gene expression. This action is exerted by binding to the PRDI (positive regulatory domain I element) of the beta-IFN gene promoter. The transcription of this gene is increased upon virus induction. Two alternatively spliced transcript variants that encode different isoforms have been reported. |
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