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1.J Immunol. 2001 May 1;166(9):5675-80. 2.J Immunol. 2003 Sep 1;171(5):2485-95.This gene encodes a member of the CD2 family of cell surface proteins involved in lymphocyte activation. These proteins are characterized by Ig domains. This protein is expressed in lymphoid tissues, and studies of a similar protein in mouse suggest that it may function during B cell lineage commitment. The gene is found in a region of chromosome 1 containing many CD2 genes. |