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1.Proc Natl Acad Sci U S A. 2011 Dec 13;108(50):20119-24. 2.Mol Cancer Res. 2010 Jun;8(6):907-18. This gene encodes a protein that acts as a repressor of beta-interferon gene expression. The protein binds specifically to the PRDI (positive regulatory domain I element) of the beta-IFN gene promoter. Transcription of this gene increases upon virus induction. Two alternatively spliced transcript variants that encode different isoforms have been reported.
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