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1.PLoS One. 2015 Jun 22;10(6):e0131086. 2.Biochem Pharmacol. 2011 Nov 1;82(9):1153-62. This gene encodes a cytokine receptor that belongs to the interleukin-1 receptor family. The encoded protein is a receptor for interleukin-1 alpha, interleukin-1 beta, and interleukin-1 receptor antagonist. It is an important mediator involved in many cytokine-induced immune and inflammatory responses. This gene is located in a cluster of related cytokine receptor genes on chromosome 2q12.
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